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    "inLanguage":"eng",
    
    "name": "Data from: Ancient and modern genomes reveal microsatellites maintain a dynamic equilibrium through deep time",

    
    "alternateName": [
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    "dateCreated": [
    
      "2024-05-08T14:10:10"],
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    "datePublished": [
    
      "2024-02-09T00:00:00"],
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    "description": "Microsatellites are widely used in population genetics, but their evolutionary dynamics remain poorly understood. It is unclear whether microsatellite loci drift in length over time. This is important because the mutation processes that underlie these important genetic markers are central to the evolutionary models that employ microsatellites. We identify more than 27 million microsatellites using a novel and unique dataset of modern and ancient Ad\u00E9lie penguin genomes along with data from 63 published chordate genomes. We investigate microsatellite evolutionary dynamics over two time scales: one based on Ad\u00E9lie penguin samples dating to approximately 46.5 kya, the other dating to the diversification of chordates more than 500 Mya. We show that the process of microsatellite allele length evolution is at dynamic equilibrium; while there is length polymorphism among individuals, the length distribution for a given locus remains stable. Many microsatellites persist over very long time scales, particularly in exons and regulatory sequences. These often retain length variability, suggesting that they may play a role in maintaining phenotypic variation within populations.\n\nFurther details are provided at: \nBennet J McComish, Michael A Charleston, Matthew Parks, Carlo Baroni, Maria Cristina Salvatore, Ruiqiang Li, Guojie Zhang, Craig D Millar, Barbara R Holland, David M Lambert, Ancient and Modern Genomes Reveal Microsatellites Maintain a Dynamic Equilibrium Through Deep Time, Genome Biology and Evolution, Volume 16, Issue 3, March 2024, evae017, https:\/\/doi.org\/10.1093\/gbe\/evae017\n\nGET DATA: https:\/\/doi.org\/10.5061\/dryad.7gt3rg2",

    
    
    
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    "keywords":[
    "PYGOSCELIS ADELIAE","MICROSATELLITES","POPULATION GENETICS","CAPE ADARE","CAPE BIRD","COULMAN ISLAND","INEXPRESSIBLE ISLAND","TORGERSON ISLAND","PENGUINS","LABORATORY","Biopsy","ANTARCTICA"
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            ,"name": "McComish, Bennet."
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    ,"temporalCoverage": [
    
      "2024-02-09T00:00:00/2024-02-09T00:00:00"
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      ,"license": [
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    , "citation": "McComish, Bennet.,  (
    2024
    ) Data from: Ancient and modern genomes reveal microsatellites maintain a dynamic equilibrium through deep time.
    Dryad.
        https://doi.org/10.5061/dryad.7gt3rg2,
    Accessed: 2026-07-07+12:00"

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